Jane has ________ knowledge about this subject. I think she should ask her teacher for further information. A. little B. few C. a little D. a few

The correct answer is A. little. The sentence should read: "Jane has little knowledge about this subject. I think she should ask her teacher for further information." "Little" and "a little" are used with uncountable nouns, while "few" and "a few" are used with countable nouns. In this case, "knowledge" is an uncountable noun, so we use "little". The difference between "little" and "a little" is that "little" means almost none or not much, which fits the context of the sentence, while "a little" means some but not much.